Thesis

Street consensus, scenarios, merits, risks, and invalidation triggers

AI-assisted
Thesis Summary

Tempus entered the second half of 2026 with strong operating momentum: second-quarter revenue increased 22%, oncology test volume increased 31%, Insights revenue increased 36%, and adjusted EBITDA turned positive. The company also raised its revenue outlook, expanded its FDA-cleared product portfolio, and demonstrated the breadth of its multimodal AI assets through PRISM2. These merits are balanced by execution risk around the proposed Personalis acquisition, the modest scale of adjusted profitability, significant stock-based compensation, and uncertainty over commercial adoption of newly cleared products.

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This section is the 12-month view: analyst targets and the probability-weighted scenarios built from them. The intrinsic value at the top of this page answers a different question: what the business is worth today.
Street view · analyst 12-month targets14 analysts · as of 18 Aug 2026
Low · most bearish analyst$35.00
Mean target$62.64
High · most bullish analyst$100.00
Our research · scenarios, merits, risks, and invalidation triggersResearch as of 2 Sep 2026
Scenarios · 12-month scenario targetsAnchored at research date
Bear CaseDownside scenario
$35.0019%

The downside case centers on revenue or adjusted EBITDA falling below guidance, oncology volume growth decelerating materially, newly cleared products commercializing more slowly than expected, or Personalis introducing transaction and integration pressure without commensurate MRD growth. The quality of reported GAAP earnings also warrants caution because second-quarter net income included a large unrealized securities gain.

Base CaseCentral scenario
$62.6457%
Matches the consensus mean

The base case assumes Tempus delivers revenue within its $1.595-$1.605 billion FY2026 guidance range and approximately $65 million of adjusted EBITDA while oncology testing and Insights remain the principal growth engines. It also assumes the Personalis transaction progresses broadly within management's stated late-Q4-2026 or early-2027 timeframe.

Bull CaseUpside scenario
$100.0024%

The upside case requires Tempus to sustain strong oncology and data-licensing growth, convert its approximately $200 million of second-quarter Data and Applications bookings into revenue, commercialize newly cleared products, and integrate Personalis successfully. Continued operating leverage beyond the current adjusted-EBITDA guidance would strengthen this case.

Scenarios are anchored to street consensus at the research date, with our probabilities and rationale.

Key Investment Merits
  • Tempus reported 31% year-over-year oncology volume growth and 36% Insights revenue growth in Q2 2026, demonstrating momentum in its two highlighted growth engines.
  • Q2 2026 adjusted EBITDA was positive at $8 million, and management maintained approximately $65 million of adjusted EBITDA guidance while raising FY2026 revenue guidance.
  • The platform continued to broaden through tumor-only xT CDx approval, delivery of an oncology foundation model to AstraZeneca, publication of PRISM2 results, and FDA clearance of ECG-PH.
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Key Investment Risks
  • The proposed Personalis acquisition carries transaction and integration risk; management described an approximately $1.5 billion enterprise value and excluded the transaction's impact from current guidance.
  • Q2 GAAP net income included $98.5 million of unrealized gains on marketable securities, while stock compensation and related payroll taxes were $55.6 million, limiting the usefulness of reported net income as an operating-performance signal.
  • FDA clearance and research performance do not ensure adoption or material revenue; ECG-PH is not a stand-alone diagnostic tool, and commercialization remains subject to clinical workflow, reimbursement, regulatory, and competitive factors.
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All scenarios are estimates and subject to change. Past performance is not indicative of future results.

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AI-assisted, source-linked narrative; figures from company filings (SEC EDGAR) and market data. Dates shown per section. Not investment advice. Terms of Use.