Thesis

Street consensus, scenarios, merits, risks, and invalidation triggers

AI-assisted
Thesis Summary

Lilly has exceptional operating momentum: second-quarter 2026 revenue reached $22.974 billion, increased 48% year over year, and prompted an increase in full-year revenue guidance to $85-$87 billion. Mounjaro and Zepbound remain the principal growth engines, while Foundayo, retatrutide and additional manufacturing capacity broaden the long-term opportunity. The August 2026 cardiovascular-risk indication for Mounjaro strengthens its clinical differentiation.

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This section is the 12-month view: analyst targets and the probability-weighted scenarios built from them. The intrinsic value at the top of this page answers a different question: what the business is worth today.
Street view · analyst 12-month targets28 analysts · as of 18 Aug 2026
Low · most bearish analyst$850.00
Mean target$1,310.90
High · most bullish analyst$1,600.00
Our research · scenarios, merits, risks, and invalidation triggersResearch as of 18 Sep 2026
Scenarios · 12-month scenario targetsAnchored at research date
Bear CaseDownside scenario
$850.0018%

Revenue falls below the $85 billion guidance floor because pricing pressure intensifies, Mounjaro or Zepbound growth slows materially, or manufacturing, regulatory, safety or pipeline setbacks constrain supply and demand. Dependence on a relatively limited group of products magnifies the effect of any cardiometabolic disruption.

Base CaseCentral scenario
$1,310.9058%
Matches the consensus mean

Lilly delivers within its $85-$87 billion 2026 revenue guidance. Cardiometabolic volume growth remains strong but is partly offset by lower realized prices, while Foundayo and other launches diversify growth gradually and manufacturing investments support supply.

Bull CaseUpside scenario
$1,600.0024%

Revenue reaches or exceeds the $87 billion upper end of 2026 guidance as Mounjaro and Zepbound sustain strong volume growth, Mounjaro's cardiovascular indication expands eligible demand, Foundayo scales from its initial launch quarter, and manufacturing capacity comes online without material delays. Retatrutide's completed Phase 3 obesity data package provides another potential cardiometabolic growth layer.

Scenarios are anchored to street consensus at the research date, with our probabilities and rationale.

Key Investment Merits
  • Second-quarter 2026 revenue increased 48% to $22.974 billion, and Lilly raised full-year revenue guidance to $85-$87 billion.
  • Mounjaro generated $9.943 billion of second-quarter revenue, increased 91% year over year, and subsequently received an FDA indication to reduce major cardiovascular-event risk in high-risk adults with type 2 diabetes.
  • Growth optionality extends beyond current injectable incretins: Foundayo recorded $98 million in its initial reported quarter, the retatrutide Phase 3 obesity data package was completed, and Lilly committed an additional $4.5 billion to Indiana manufacturing.
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Key Investment Risks
  • Growth is concentrated in Mounjaro and Zepbound, which together drove much of the quarter's expansion; disruption to either franchise could materially affect results.
  • Worldwide volume increased 60% in the second quarter, but realized prices declined 13%, demonstrating that pricing and reimbursement pressure can offset part of demand growth.
  • The outlook depends on successful manufacturing expansion, regulatory execution, clinical outcomes and integration of multiple business-development transactions, all of which Lilly identifies as uncertain.
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All scenarios are estimates and subject to change. Past performance is not indicative of future results.

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AI-assisted, source-linked narrative; figures from company filings (SEC EDGAR) and market data. Dates shown per section. Not investment advice. Terms of Use.